Complete molecular cloning solutions from design to delivery
Our Cloning Services provide end-to-end molecular cloning solutions backed by 20+ years of drug discovery experience. From simple subcloning to complex multi-fragment assemblies, we deliver sequence-verified constructs on time, every time.
We specialize in challenging projects that others can't handle—GC-rich sequences, repetitive elements, toxic genes, and complex multi-component systems. Our proprietary methods cut delivery times in half while maintaining 100% sequence accuracy.
All cloning projects start with a consultation to ensure we understand your goals and design the optimal approach. Whether you need a single construct or a library of thousands, we're your local partner for reliable molecular cloning.
Comprehensive services for every cloning need
De-novo synthesis up to 1 kb with seamless insertion into any vector. Codon-optimized and error-proofed using our trade-secret methods that cut delivery time in half.
Gibson/NEBuilder assembly of 2-6 fragments into vectors up to 14 kb total. We handle complex assemblies including multi-insert into separate sites.
Precise point, deletion, and insertion mutations with our low-fail rate workflow. Price scales with variant count for efficient SAR campaigns.
Mini to Giga scale preparations with full sequence verification. Endotoxin-free options available for cell culture and pre-clinical applications.
Bar-coded pooled or arrayed libraries for lentiviral, AAV, baculoviral, and CRISPR systems. Up to 25k constructs per pool with full representation validation.
Expert guidance for challenging projects. Codon optimization, troubleshooting difficult sequences, and comprehensive project planning from our experienced team.
We'll discuss your project, recommend the optimal approach, and provide a detailed quote and timeline.
Request Consultation7-10 day delivery with proprietary methods that cut typical timelines in half
20+ years experience including work on FDA-approved therapeutics
100% sequence verification and comprehensive QC documentation
Boston-based lab with in-person support and consultation
We work with any vector system you need
Supporting research across biotech and pharma
Construct generation for biologics, gene therapy vectors, and cell therapy programs with pre-clinical quality requirements.
Expression constructs, domain shuffling, and variant libraries for enzyme optimization and antibody engineering.
CRISPR libraries, ORF collections, and screening constructs for target identification and validation.
Reporter constructs, biosensors, and tool reagents for high-throughput screening and diagnostic development.
Let's discuss your needs and design the optimal approach