Multi-Fragment Assembly

Complex Gibson/NEBuilder assemblies with up to 6 fragments

≤ 10 Business Days Delivery

Master Complex Vector Construction

Our Multi-Fragment Assembly service handles the most challenging cloning projects with 2-6 Gibson/NEBuilder fragments assembled into vectors up to 14kb total size.

We specialize in complicated assemblies including multi-insert constructions into separate insertion sites. Our trade-secret GC extremes rescue method ensures success even with challenging sequences like CAG repeats.

Perfect for reshuffling vectors and inserts, creating complex expression cassettes, or building multi-component systems in a single construct.

Quick Facts

Fragment Count
2-6 fragments
Max Vector Size
14 kb
Delivery Time
≤ 10 days
Assembly Method
Gibson/NEBuilder

Service Specifications

🧬 Core Specifications

  • 2-6 Gibson/NEBuilder fragments
  • Insert fits into maximum vector size of 14kb
  • Multi-insert into separate insertion sites supported
  • Handles very complicated assemblies
  • 100% sequence verification included

Popular Add-Ons

  • Trade secret GC extremes rescue method (such as CAG)
  • Repeat-rich fragment handling
  • Seamless assembly design
  • Linker optimization

Typical Applications

Reshuffling vectors and inserts for complex constructs

Multi-Gene Expression

Construct polycistronic vectors with multiple genes, promoters, and regulatory elements for co-expression studies or metabolic pathway engineering.

Domain Shuffling

Combine functional domains from different proteins to create chimeric proteins with novel properties for therapeutic or research applications.

Complex Reporter Systems

Build multi-component reporter constructs with different fluorescent proteins, selection markers, and regulatory elements in a single vector.

Pathway Reconstruction

Assemble entire biosynthetic pathways by combining multiple enzyme-coding sequences with appropriate regulatory elements for metabolic engineering.

Ready to Start?

Get your constructs delivered on time, guaranteed