Next-Generation Sequencing

High-throughput sequencing for transcriptomics, genomics, and beyond

Consultation Required

Advanced Sequencing for Complex Questions

Our Next-Generation Sequencing (NGS) services provide the throughput and depth needed for transcriptomics, whole genome analysis, and comprehensive variant detection. We offer both Illumina and NanoPore platforms, plus combined approaches for the most accurate results.

NGS projects require careful experimental design to ensure you get the data quality and coverage needed for your specific research questions. That's why all our NGS services begin with a consultation—we'll work with you to design the optimal approach for your project.

Whether you're studying gene expression changes, characterizing a genome, or detecting structural variants, our team has the expertise to guide you from experimental design through data delivery.

Quick Facts

Platforms
Illumina & NanoPore
Applications
RNA-seq, WGS, More
First Step
Free Consultation
Location
Cambridge, MA

NGS Service Options

Choose the platform and approach that fits your research

Illumina (RNA-seq)

Short-Read

High-accuracy short-read sequencing for gene expression analysis. Industry-standard platform for transcriptomics with excellent quantification and sensitivity.

Common Applications:

  • Differential gene expression
  • Transcriptome profiling
  • Alternative splicing analysis
  • Small RNA sequencing
  • Single-cell RNA-seq

NanoPore NGS

Long-Read

Long-read sequencing for applications where read length matters. Ideal for structural variant detection, full-length transcript analysis, and de novo assembly.

Common Applications:

  • Full-length RNA sequencing
  • Whole genome sequencing
  • Structural variant detection
  • Methylation analysis
  • De novo genome assembly

Illumina + NanoPore

Hybrid Approach

Combine the accuracy of short reads with the structural resolution of long reads. The gold standard for comprehensive variant calling and genome characterization.

Common Applications:

  • Accurate variant calling
  • Complex genome assembly
  • Comprehensive transcriptomics
  • Phasing and haplotyping
  • Clinical-grade sequencing

📞 All NGS Services Require Consultation

We'll discuss your research goals, recommend the optimal approach, and provide a detailed quote tailored to your project.

Request Consultation

What to Expect

💬 Consultation Process

  • Submit your project request online
  • We'll reach out within 1 business day
  • Brief call to discuss your research goals
  • We recommend platform and parameters
  • Receive detailed quote and timeline
  • Approve and proceed when ready

📊 Deliverables

  • Raw sequencing data (FASTQ)
  • Quality control metrics and reports
  • Alignment files (BAM) if applicable
  • Analysis results per project scope
  • Secure data access via dashboard
  • Ongoing technical support

Research Applications

NGS enables discoveries across many fields

Drug Discovery

Understand drug mechanisms, identify biomarkers, and characterize cellular responses through comprehensive transcriptome profiling.

Cancer Research

Detect mutations, characterize tumor heterogeneity, and identify therapeutic targets with deep sequencing approaches.

Genetic Disease

Identify disease-causing variants, characterize rare diseases, and support diagnostic development with clinical-grade sequencing.

Microbial Genomics

Characterize microbial communities, assemble novel genomes, and study pathogen evolution with long and short-read approaches.

Ready to Discuss Your Project?

Our team will help you design the optimal NGS approach